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SA - Selective Availability, from when GPS time and ephemerides data was dithered to degrade the navigation message to nonqualified receivers.

SBIR - Small Business Innovative Research which yielded developments like the composite ballistic screen

Scramjet - Supersonic-combustion ramjet

SEPIC - Single Ended Primary Inductance Converter

SDC - Service Delivery Card

SDK - software development kit (On2 DirectShow VP8 SDK)

SISTM - Sport Integration System (Sports music system)

SOC - system-on-a-chip - as for a digital media processor

SSR - Super Self Refresh memory technology that reduces self refresh current in Elpida's DDR SDRAM

STTR - Small Business Technology Transfer (Ferrium C61 C64 alloys)

SVN - software virtual network (SVN software virtual network battlefield communication simulation)