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LAN - Local Area Network - a computer network that links devices within a building or group of adjacent buildings

LAT - Large Area Telescope (Microquasar radio-emitting gas jets)

LCROSS - Lunar Crater Observation and Sensing Satellite (Moon water)

LDL - low-density lipoproteins - bad cholesterol (Olive oil turkey)

LDW - Lane Departure Warning

LELA - Linksys EasyLink Advisor (Cisco media router)

LIN - Local Interface Network in Automotive Electronics

LTE - Long Term Evolution (Verizon 4G LTE network)